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Zepbound

Tirzepatide approved for weight management — the current weight-loss leader.

Zepbound is tirzepatide FDA-approved for chronic weight management (and for obstructive sleep apnea in adults with obesity). It's the weight-loss twin of Mounjaro.

Results

In SURMOUNT-1, tirzepatide produced up to ~20–22% average weight loss. In the head-to-head SURMOUNT-5 trial, Zepbound beat Wegovy (~20.2% vs ~13.7%). See Wegovy vs Zepbound.

Dose & side effects

Weekly injection titrated to as high as 15 mg. Side effects are mostly GI early on; boxed thyroid-tumor warning; cautions for pancreatitis and gallbladder disease.

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RN

Reviewed by a Registered Nurse

Written and reviewed by a licensed RN as general education, not personal medical advice. Always talk with your own provider before starting or changing a medication. About us →

This page is general education only, not medical advice, and does not create a nurse-patient relationship. GLP-1 medications are prescription drugs with real risks and a boxed warning for thyroid C-cell tumors; they are not right for everyone. Compounded medications are not FDA-approved. Consult a licensed provider. See our medical disclaimer.

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